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Adeno-Associated Virus Vectors: Design and Delivery
Hardcover
Series: Methods in Molecular Biology, Book 1950
Medical ReferenceOther Animals
ISBN13: 9781493991389
Publisher: Humana Pr
Published: Feb 20 2019
Pages: 426
Weight: 2.15
Height: 1.00 Width: 7.00 Depth: 10.00
Language: English
Chapter 1. Stereotactic Intraparenchymal Injection for Gene Delivery to the Brain
Chapter 2. MRI-Guided Intraparenchymal Injection for Gene Delivery to the Brain (Krystof Bankiewicz)
Chapter 3: Intravenous Infusion for Widespread Delivery to Nervous and Peripheral Tissues (Brian Kaspar)
Chapter 4: MRI-Guided Focused Ultrasound for Targeted Gene Delivery to the Brain (Isabelle Aubert)
Chapter 5: Intrathecal Infusion for Gene Delivery to the Nervous System (Mark Tuszynski and myself)
Chapter 6: Direct Intraparenchymal Injection for Gene Delivery to the Spinal Cord
Chapter 7: Retrograde Targeting of Spinal Motor Neurons by Muscle Injection
Chapter 8: Subpial Infusion for Widespread Gene Delivery to the Spinal Cord
Chapter 9: Intraganglionic Microinjection for Gene Delivery to the DRG
Chapter 10: Intravitreal Injection for Gene Delivery to the Eye
Chapter 11: Subretinal Injection for Gene Delivery to the Eye (Luk Vandenberghe)
[Chapters 10 and 11 could be combined into a single chapter for ocular delivery]
Part II: Gene Delivery to Peripheral Tissues
Chapter 12: Intranasal Administration for Gene Delivery to the Lung
Chapter 13: Orotracheal Administration for Gene Delivery to the Lung
Chapter 14: Surgical Tracheal Administration for Gene Delivery to the Lung
[Chapters 13 and 14 could be combined into a single chapter for tracheal delivery]
Chapter 15: Infusion of Coronary Artery for Global Gene Delivery to the Heart
Chapter 16: Aortic Occlusion and Pressurized Infusion for Global Gene Delivery to the Heart
[Chapters 15 and 16 could be combined into a single chapter for global heart delivery]
Chapter 17: Intramyocardial Injection for Targeted Gene Delivery to the Heart
Chapter 18: Intraportal Vein Injection for Global Gene Delivery to the Liver
Chapter 19: Intraparenchymal Injection for Targeted Gene Delivery to the Liver
Chapter 20: Gene Delivery to the Spleen
Chapter 21: Gene Delivery to the Kidney
Chapter 22: Gene Delivery to Skeletal Muscle
Part III: Design of Novel Vectors for Targeting of Specific Tissues and Cell Types
Chapter 23: Design of AAV vectors for Delivery of Large or Multiple Transgenes
Chapter 24: Design of AAV vectors for Delivery of RNAi
Chapter 25: Altering AAV tropism with Directed Evolution
Chapter 26: Altering AAV tropism with AAV-CREATE (Ben Deverman)
Chapter 27: Altering AAV tropism with Phage Display (Tomas Bjorklund)
Chapter 28: Minipromoters for Tissue- and Cell-Specific Gene Expression (Elizabeth Simpson)
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