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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Autophagy in Stem Cell Maintenance and Differentiation

Autophagy in Stem Cell Maintenance and Differentiation

Shravage, Bhupendra V.
Turksen, Kursad

Paperback

Series: Stem Cell Biology and Regenerative Medicine, Book 73

Medical ReferenceBiology

ISBN10: 3031173643
ISBN13: 9783031173646
Publisher: Springer Nature
Published: Nov 10 2023
Pages: 288
Weight: 0.93
Height: 0.62 Width: 6.14 Depth: 9.21
Language: English
This book covers a wide range of topics that illustrate the various functions of autophagy in stem cells and offers insights on the mechanisms by which autophagy can regulate stem-cell self-renewal and facilitate specific differentiation programs. Stem cells are unique cells present in most multicellular animals and are essential for their survival. They have two unique properties: the ability to self-renew and the ability to differentiate into one or more cell types. These characteristics of stem cells have found immense therapeutic potential in regenerative medicine. Autophagy is a crucial membrane trafficking pathway that is essential for maintaining cellular homeostasis that involves sequestration of non-functional proteins, protein aggregates and damaged organelles in double-membraned vesicles called autophagosomes, which are subsequently targeted to the lysosome for degradation. The primary aim of this book is to provide knowledge of recent developments in our understanding of the role of autophagy in stem cells, including germline stem cells.

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