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Apoptosis Techniques and Protocols

Apoptosis Techniques and Protocols

Hardcover

Series: Neuromethods, Book 37

Medical ReferenceAnatomy & Physiology

ISBN10: 1588290123
ISBN13: 9781588290120
Publisher: Springer Nature
Published: Feb 12 2002
Pages: 250
Weight: 1.26
Height: 0.93 Width: 6.90 Depth: 8.80
Language: English
In this revised and expanded second edition, seasoned experts describe in step-by-step detail their best state-of-the-art techniques for studying neuronal cell death. These readily reproducible methods solve a wide variety of research problems, including the detection of the key proteins involved in neuronal apoptosis (Bax protein, cytochrome c, and caspases), the direct assessment of the role of pro-apoptotic proteins in neurons by viral infections and microinjections, and the detection of pro-apoptotic proteins in situ. There are also hands-on methods for the study of apoptosis mechanisms in neuronal compartments, for studying synaptosis, and for establishing gene expression profiles in neurodegenerative brain tissues by using DNA microarrays.

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