Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Antibody Drug Conjugates: Design, Discovery, and Development

Antibody Drug Conjugates: Design, Discovery, and Development

Gukasyan, Hovhannes J.
Kulkarni, Ashutosh

Hardcover

Series: Aaps Advances in the Pharmaceutical Sciences, Book 52

Medical ReferenceChemistry

Currently unavailable to order

ISBN10: 3031893182
ISBN13: 9783031893186
Publisher: Springer
Published: Jan 3 2026
Pages: 232
Weight: 1.08
Height: 0.78 Width: 6.42 Depth: 9.33
Language: English

This volume ​provides a comprehensive recapitulation of structure-activity relationship (SAR) from a mechanism of action point of view for this unique therapeutic modality, in a largely disease agnostic manner. From a disease biology and pharmacology perspective, the cellular target and drug-conjugate selection, considerations on liker -chemistry and -antibody ratio, and formulation science and technology, to get from bench to bedside (i.e. from a laboratory to the systemic circulation in a patient). The book also provides an understanding around target binding and drug/payload release mechanisms. Furthermore, pharmacokinetic and safety pharmacological aspects from a regulatory and clinical perspective are discussed, along with current chemistry, manufacturing, controls guidance and emerging novel delivery devices or technologies.

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