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Animal Models of T Cell-Mediated Skin Diseases

Animal Models of T Cell-Mediated Skin Diseases

Paperback

Series: Ernst Schering Foundation Symposium Proceedings, Book 50

Medical ReferenceBiology

ISBN10: 3642422055
ISBN13: 9783642422058
Publisher: Springer Nature
Published: Dec 3 2014
Pages: 291
Weight: 0.97
Height: 0.65 Width: 6.14 Depth: 9.21
Language: English

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The 50th International Workshop of the Ernst Schering Research Foundation focussed on Animal Models of T Cell-Mediated Skin Diseases. Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.

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