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Alzheimer's Disease: Methods and Protocols

Alzheimer's Disease: Methods and Protocols

Paperback

Series: Methods in Molecular Biology, Book 2561

Medical ReferenceCognition

ISBN10: 1071626574
ISBN13: 9781071626573
Publisher: Humana
Published: Nov 19 2023
Pages: 340
Weight: 1.36
Height: 0.74 Width: 7.00 Depth: 10.00
Language: English
This volume explores the latest techniques used to study the human brain towards understanding Alzheimer's Disease and related neurodegenerative disorders. Contributed to by world-renowned experts, the chapters in this book are divided into five parts. Part One discusses human post-mortem brain preparations including single-cell isolation and use of specialized imaging. Part Two talks about neural cellular models using primary and human induced pluripotent stem cells to model aspects of the human brain. Part Three details nucleic acid analyses including transcriptomic and somatic genomic changes, and Part Four discusses lipid analyses via mass spectrometry. Lastly, Part Five covers protein analyses, particularly Aβ and Tau. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, andtips on troubleshooting and avoiding known pitfalls.

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