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AIDS Pathogenesis

AIDS Pathogenesis

Hardcover

Series: Immunology and Medicine, Book 28

Medical Reference

ISBN10: 0792361962
ISBN13: 9780792361961
Publisher: Springer Nature
Published: Mar 31 2000
Pages: 284
Weight: 1.31
Height: 0.69 Width: 6.14 Depth: 9.21
Language: English
Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS).
The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

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