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Advances in Chromatographic Techniques for Therapeutic Drug Monitoring
Hardcover
ISBN13: 9781420067583
Publisher: Crc Pr Inc
Published: Oct 6 2009
Pages: 476
Weight: 2.23
Height: 1.20 Width: 7.04 Depth: 10.37
Language: English
For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for implementing chromatographic methods, this volume describes the theory and application of therapeutic drug monitoring in clinical laboratories. It addresses preanalytical variables, the pitfalls of immunoassays, tandem mass spectrometry, issues related to pain management and herbal supplements, and drug monitoring for a range of medications.
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