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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Addiction, Second Edition

Addiction, Second Edition

Kenny, Paul J.
Pierce, R. Christopher
Unterwald, Ellen

Hardcover

Series: Perspectives Cshl

Medical ReferenceAnatomy & Physiology

Currently unavailable to order

ISBN10: 1621823504
ISBN13: 9781621823506
Publisher: Cold Spring Harbor Laboratory Press
Published: Sep 30 2020
Pages: 404
Weight: 2.55
Height: 0.90 Width: 7.20 Depth: 10.10
Language: English
Addiction to psychoactive drugs found in cigarettes, alcoholic drinks, and opioid analgesics is a severe problem for society. Events associated with addiction-drug abuse, dependence, withdrawal, and relapse-involve complex neurobiological changes in the brain. To develop effective long-term treatment strategies for substance use disorders, a more complete understanding of these brain changes is needed.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine provides a comprehensive update on our understanding of the biological basis of and treatment strategies for addiction to psychoactive drugs, with an emphasis on opioids. Contributors examine the molecular targets of alcohol, cannabinoids, nicotine, stimulants, and opioids, the resulting changes to the neurocircuitry, and various genetic, environmental, developmental, and behavioral factors that influence the progression from abuse to addiction and susceptibility to relapse. Advances in animal models of addictive behavior and single-cell strategies to dissect neural circuits are also described.

In addition, the authors review compounds currently used or under development to treat substance use disorders, their pharmacological mechanisms, and challenges related to preclinical testing in animal models. This volume is an indispensable reference for all neuroscientists and those who are interested in understanding and reducing the public health burden of drug addiction.

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