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Acute Promyelitic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy

Acute Promyelitic Leukemia: Molecular Genetics, Mouse Models and Targeted Therapy

Hardcover

Series: Current Topics in Microbiology and Immmunology, Book 313

Medical Reference

ISBN10: 3540345922
ISBN13: 9783540345923
Publisher: Springer
Published: Dec 13 2006
Pages: 274
Weight: 1.16
Height: 0.63 Width: 6.36 Depth: 9.36
Language: English
Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.

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Medical Reference