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Activating and Inhibitory Immunoglobulin-Like Receptors

Activating and Inhibitory Immunoglobulin-Like Receptors

Paperback

Medical ReferenceBiologyChemistry

ISBN10: 4431679596
ISBN13: 9784431679592
Publisher: Springer Nature
Published: Nov 15 2012
Pages: 246
Weight: 0.81
Height: 0.55 Width: 6.14 Depth: 9.21
Language: English
A remarkable spectrum of novel immunoreceptors sharing related immunoglobulin-like domains and signaling potential has been identified in recent years. These receptors have attracted widespread interest because they resemble the TCR, BCR, and FcR complexes in their ability to serve as activating or inhibitory receptors on the cells that bear them. Moreover, they are well positioned to affect both innate and adaptive immunity. The full range of ligands for these new receptor families is still not known, and understanding of their physiological roles is far from complete. This volume is the first attempt to summarize and highlight all known aspects of immunoglobulin-like receptors, providing a topical overview of the roles and characteristic features of the immunoglobulin-like receptors and related molecules in the immune system. Researchers in immunology, molecular biology, cell biology, clinical medicine, and pharmacology will find this book invaluable.

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