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Therapeutic Applications of Dopamine D3 Receptor Function: New Insight After 30 Years of Research
Paperback
Series: Current Topics in Behavioral Neurosciences, Book 60
ISBN13: 9783031230608
Publisher: Springer Nature
Published: Jan 4 2024
Pages: 275
Weight: 0.88
Height: 0.60 Width: 6.14 Depth: 9.21
Language: English
The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
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