Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Systems Pharmacology and Pharmacodynamics

Systems Pharmacology and Pharmacodynamics

Mager, Donald E.
Kimko, Holly H. C.

Hardcover

Series: Aaps Advances in the Pharmaceutical Sciences, Book 23

Medical ReferenceGeneral Mathematics

ISBN10: 3319445324
ISBN13: 9783319445328
Publisher: Springer Nature
Published: Dec 16 2016
Pages: 511
Weight: 2.01
Height: 1.13 Width: 6.14 Depth: 9.21
Language: English
While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from systems biology and pharmacodynamics researchers, describing how systems pharmacology may be developed and refined further to show practical applications in drug development. There is a growing awareness that pharmaceutical companies should reduce the high attrition in the pipeline due to insufficient efficacy or toxicity found in proof-of-concept and/or Phase II studies. Systems Pharmacology and Pharmacodynamics discusses the framework for integrating information obtained from understanding physiological/pathological pathways (normal body function system vs. perturbed system due to disease) and pharmacological targets in order to predict clinical efficacy and adverse events through iterations between mathematical modeling and experimentation.

Also in

Medical Reference

View All