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Pharmaco Modeling w/NONMEM

Pharmaco Modeling w/NONMEM

Hardcover

Medical ReferenceProbability & Statistics

ISBN10: 0470582294
ISBN13: 9780470582299
Publisher: John Wiley & Sons
Published: Jun 27 2014
Pages: 320
Weight: 1.25
Height: 0.90 Width: 6.40 Depth: 9.30
Language: English
This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.
- Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects
- Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model building process and applications of empirical Bayesian estimates in the drug development environment
- Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control
- Has datasets, programming code, and practice exercises with solutions, available on a supplementary website

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