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    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
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The Ontogenesis of Cortical Circuitry: The Spatial Distribution of Synapses in Somesthetic Cortex of Newborn Dog

The Ontogenesis of Cortical Circuitry: The Spatial Distribution of Synapses in Somesthetic Cortex of Newborn Dog

Molliver, M. E.
Loos, H. Van Der

Paperback

Series: Advances in Anatomy, Embryology and Cell Biology, Book 42

Medical Reference

ISBN10: 3540047972
ISBN13: 9783540047971
Publisher: Springer Nature
Published: Jan 1 1970
Pages: 54
Weight: 0.24
Height: 0.12 Width: 6.69 Depth: 9.61
Language: English
The ontogenesis of cortical circuitry is the subject of the investigation reported in this paper!. Strategie elements of cortical circuitry are synaptic contacts: sites of neuronal interaction. If we first determine the location of early formed synap- ses, we may then seek the pre-and postsynaptic elements, that is, the structures which meet and interact at each synaptic junction. The dynamic aspects of cortical development cannot be studied directly: neuronal growth cannot be observed in an intact brain. The pattern of develop- ment can be approached only by the analysis of static properties at multiple ages. We have selected the newborn dog as a starting point for these studies. Our observations have been restricted to a small portion of primary somesthetic cor- tex. This region was selected because, in mature cortex, its input and physiologie properties are relatively weIl known. It is particularly advantageous to study a primary sensory projection area because its morphologie development can be di- rectly related to its functional development. (A related investigation of the onto- genesis of electrical activity in somesthetic cortex of the dog will be reported separately). A selective review of the literature is necessary in order to place this work in the context of a few relevant phenomena of cortical development.

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