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Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis

Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis

Paperback

Medical ReferenceGenetics

ISBN10: 1461350255
ISBN13: 9781461350255
Publisher: Springer Nature
Published: Oct 23 2012
Pages: 335
Weight: 1.09
Height: 0.73 Width: 6.14 Depth: 9.21
Language: English
It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.

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