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Geni e tubercolosi
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ISBN10: 663005301X
ISBN13: 9786630053012
Publisher: Edizioni Sapienza
Published: May 30 2026
Pages: 76
Weight: 0.25
Height: 0.18 Width: 6.00 Depth: 9.00
Language: Italian
ISBN13: 9786630053012
Publisher: Edizioni Sapienza
Published: May 30 2026
Pages: 76
Weight: 0.25
Height: 0.18 Width: 6.00 Depth: 9.00
Language: Italian
La tubercolosi (TB) è una malattia infettiva che colpisce tipicamente i polmoni e altre parti del corpo umano. Diversi fattori di rischio sono stati associati alla TB e studi epidemiologici suggeriscono che i fattori genetici umani svolgano un ruolo importante nella suscettibilità , nella protezione, nella progressione e nell'esito della TB. Questo libro tratta ampiamente i fattori genetici umani, concentrandosi sui polimorfismi a singolo nucleotide nel gene del recettore del mannosio, della proteina DC-SIGN (ICAM-3-grabbing nonintegrin specifica per le cellule dendritiche), del recettore toll-like, del recettore del complemento 3, del dominio di oligomerizzazione dei nucleotidi 2, del recettore nucleare della vitamina D, del recettore purinergico P2X7, del CD14, proteina tensioattiva A, lectina legante il mannosio, fattore di necrosi tumorale alfa, interferone-gamma, interleuchina (IL)-12, IL-10, IL-6, IL-18, IL-1β, IL-8, antagonista del recettore dell'IL-1 (IL-1RA), proteina chemoattrattiva dei monociti 1, RANTES (CCL5), CXCL10, ossido nitrico sintasi inducibile e proteina trasportatrice di soluti 11A1.
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