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Gènes et tuberculose
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ISBN10: 6630050452
ISBN13: 9786630050455
Publisher: Editions Notre Savoir
Published: May 31 2026
Pages: 80
Weight: 0.26
Height: 0.19 Width: 6.00 Depth: 9.00
Language: French
ISBN13: 9786630050455
Publisher: Editions Notre Savoir
Published: May 31 2026
Pages: 80
Weight: 0.26
Height: 0.19 Width: 6.00 Depth: 9.00
Language: French
La tuberculose (TB) est une maladie infectieuse qui touche généralement les poumons et d'autres parties du corps humain. Divers facteurs de risque ont été associés à la tuberculose et des études épidémiologiques suggèrent que les facteurs génétiques humains jouent un rôle important dans la susceptibilité, la protection, la progression et l'issue de la tuberculose. Cet ouvrage traite en détail des facteurs génétiques humains, en se concentrant sur les polymorphismes nucléotidiques simples dans les gènes du récepteur du mannose, de la protéine DC-SIGN (ICAM-3-grabbing nonintegrin spécifique des cellules dendritiques), du récepteur Toll-like, du récepteur du complément 3, du domaine d'oligomérisation des nucléotides 2, du récepteur nucléaire de la vitamine D, du récepteur purinergique P2X7, du CD14, la protéine tensioactive A, la lectine liant le mannose, le facteur de nécrose tumorale alpha, l'interféron gamma, l'interleukine (IL)-12, IL-10, IL-6, IL-18, IL-1β, IL-8, l'antagoniste du récepteur de l'IL-1 (IL-1RA), la protéine chimioattractive des monocytes 1, le RANTES (CCL5), le CXCL10, la synthase inductible de l'oxyde nitrique et la protéine de transport de solutés 11A1.
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