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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Investigation of Cytokine Gene Polymorphism in Dengue Hemorrhagic Fever

Investigation of Cytokine Gene Polymorphism in Dengue Hemorrhagic Fever

Silva, Francisco Marcio Pereira Da
Valença, José Telmo, Jr.

Paperback

Medical Reference

ISBN10: 6208491363
ISBN13: 9786208491369
Publisher: Our Knowledge Publishing
Published: Aug 29 2025
Pages: 52
Weight: 0.18
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
Observing the current context in relation to the lack of control of successive dengue epidemics in Brazil, as well as the rapid territorial expansion of Aedes Aegypti, we foresee the possibility of outbreaks and/or epidemics of Dengue Hemorrhagic Fever (DHF), and as a result, we will also see an increase in its lethality, given the current situation of our national health system. We know that some diseases present different immune responses in the face of polymorphism in cytokine genes. In this study, we seek to identify genetic factors related to the worsening of the disease in patients with DHF. This investigation focuses on the possibility of polymorphism in cytokine genes: TNF-α -308 G→A, TGF-β codon 10 and codon 25, IL-10 -1082 G→A, -819 C→T, -592 A→C, IL-6 -174G→C, and IFN-γ +874 T→A with FHD. We hope to contribute to the discovery of new paths in the search for a better understanding of this pathology that affects thousands of people worldwide.

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