Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Green TiO2 as Nanocarriers for Targeting Cervical Cancer Cell Lines

Green TiO2 as Nanocarriers for Targeting Cervical Cancer Cell Lines

Sadasivam, Senthilkumaar

Paperback

Medical Reference

ISBN10: 1543700616
ISBN13: 9781543700619
Publisher: Partridge Pub
Published: Jul 14 2017
Pages: 110
Weight: 0.35
Height: 0.23 Width: 6.00 Depth: 9.00
Language: English

Nanoparticles have received much attention recently due to their use in cancer therapy. Studies have shown that different metal oxide nanoparticles induce cytototoxicity in cancer cells. Drug delivery systems are designed to achieve drug therapeutic index and enhance the efficacy of controlled drug release targeting with specificity and selectivity by successful delivery of therapeutic agents at the desired sites without affecting the non-diseased neighbouring cells or tissues. In this work, nano-titanium dioxide, as anatase phase, was obtained by the sol-gel method with a cleaner technology a bio-extract obtained from the plant Artemisia pallens containing poly alcohols- used as a solvent, the structural, optical, particle size and the morphological properties of TiO2 nanoparticles were analyzed using x-ray diffraction data, scanning electron microscope. The green TiO2 nanoparticles had a bandgap of 3.2 eV. The fourier transformer infra red spectroscopy (FT-IR) shows a single band attributed to TiO2 using the simple aqueous based organic solvent free approach is further used as nano carriers for drug delivery system. Also we have developed and demonstrated a bio-based titanium dioxide that can be loaded with anticancer drug and selectively deliver it to cancer cells with high specificity by achieving the effective cervical cancer cell death without inducing specific toxicity. The study showed that the DOX loaded TiO2 nanocrystals has promising applications in delivery of anticancer drugs.

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