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Apoptosis Methods in Pharmacology and Toxicology: Approaches to Measurement and Quantification

Apoptosis Methods in Pharmacology and Toxicology: Approaches to Measurement and Quantification

Hardcover

Series: Methods in Pharmacology and Toxicology

Medical ReferenceAnatomy & Physiology

ISBN10: 0896038904
ISBN13: 9780896038905
Publisher: Springer Nature
Published: Jun 25 2002
Pages: 156
Weight: 0.98
Height: 0.69 Width: 6.24 Depth: 9.24
Language: English
Dr. Myrtle A. Davis has assembled a panel of cutting-edge scientists to describe their best methods for detecting, illuminating, and quantifying apoptotic mechanisms in a way that is useful for the design of toxicology and pharmacology studies. These state-of-the-art techniques include flow cytometric, fluorometric, and laser scanning methods for quantifying and characterizing apoptosis, as well as protocols for the use of DNA microarray technology, high throughput screens, and ELISA. Immunocytochemical methods for measuring biochemical and molecular endpoints in tissue sections will be highly useful for those carrying out studies in whole animal models as opposed to cell culture systems.

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