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Studies on the Synthesis of Fused Primidine Derivatives

Studies on the Synthesis of Fused Primidine Derivatives

Paperback

Chemistry

Currently unavailable to order

ISBN10: 3330846771
ISBN13: 9783330846777
Publisher: Justfiction Ed
Published: Oct 4 2019
Pages: 52
Weight: 0.20
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
INTRODUCTION Pyrimidine Pyrimidine (1) is the trivial name for 1,3-diazine: two meta oriental CH units in benzene have been replaced by nitrogen atom. Pyrimidine has one axis of symmetry about the C2-C5 axis, it has three different pairs of bond lengths and four different bond angles. Accordingly in 1H and 13C-NMR spectra the 1H and 13C nuclei are found at three different chemical shifts. Biological activity of pyrimidines: Pyrimidine derivatives and heterocyclic annelated pyrimidines continue to attract great interest due to the wide variety of interesting biological activities and therapeutic applications [Segal et al., 1962][Cumming et al., 2004] such as anticonvulsant [Tripathi et al., 1981], analgesic [Pemmsin et al., 1988], antihypertensive [Cammito et al., 1990], antipyretic [Smith et al., 1964], antiviral [Balzarini et al., 2002], anti-inflammatory drugs [Nega et al., 1990], bactericidal [Mastafanova et al., 1982], fungicidal [Zhikhareva et al., 1976]. As well as, they are used in agriculture as pesticides [Tetsuo et al., 1987] and plant growth regulators [Shishoo and Jain, 1992].

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