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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Optimization of Synthesis and Quality Control Procedures for the Preparation of 18f and 123i Labelled Peptides for Nuclear Medicine

Optimization of Synthesis and Quality Control Procedures for the Preparation of 18f and 123i Labelled Peptides for Nuclear Medicine

International Atomic Energy Agency

Paperback

Series: IAEA Tecdoc

Physics

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ISBN10: 9201168020
ISBN13: 9789201168023
Publisher: International Atomic Energy Agency
Published: Aug 30 2002
Pages: 277
Language: English
This publication describes the general scope of a Co-ordinated Research Project focused on the optimization of syntheses, quality control, in vitro and in vivo evaluation of F-18 and I-123 radiopharmaceuticals based on peptides with known or anticipated clinical potential. Selective labelling procedures using prosthetic groups were applied to both fluorine and iodine. Studies included investigation on the fate of the label, stability in vivo, biodistribution and pharmacokinetic studies in rodents and in cell culture. With respect to I-123, the work aimed at development of a simplified labelling kit using solid state systems.

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