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Noninferiority Testing in Clinical Trials: Issues and Challenges
Paperback
Series: Chapman & Hall/CRC Biostatistics
Health GeneralMedical ReferenceProbability & Statistics
ISBN13: 9780367576028
Publisher: CRC Press
Published: Jun 30 2020
Pages: 208
Weight: 0.66
Height: 0.44 Width: 6.14 Depth: 9.21
Language: English
Requiring no prior knowledge of NI testing, this book explains how to choose the NI margin as a small fraction of the therapeutic effect of the active control in a clinical trial. It discusses issues with estimating the effect size based on historical placebo control trials of the active control. The author covers basic concepts related to NI tr
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