Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Heterocyclic Sulfonamides: Design, Synthesis and Biological Evaluation

Heterocyclic Sulfonamides: Design, Synthesis and Biological Evaluation

El-Saghier, Ahmed M. M.
Enaili, Souhaila S.

Paperback

Chemistry

ISBN10: 6209967817
ISBN13: 9786209967818
Publisher: LAP Lambert Academic Publishing
Published: May 15 2026
Pages: 384
Weight: 1.13
Height: 0.85 Width: 6.00 Depth: 9.00
Language: English
This book presents the design and synthesis of novel bioactive heterocyclic compounds derived from N-(sulfamoylphenyl)acetamides. The main objective is to develop compounds with potential insecticidal and anti-inflammatory activities while maintaining low toxicity and environmental safety. Various heterocyclic derivatives, including thiadiazoles, thiadiazines, spiro compounds, and triazolotriazines, were synthesized using efficient and green chemical methods. The structures of the synthesized compounds were confirmed through spectroscopic techniques. The biological evaluation demonstrated promising insecticidal activity against Spodoptera littoralis, where several compounds showed strong toxicity. Additionally, anti-inflammatory activity was assessed using different in vitro methods, indicating significant potential for some derivatives. Molecular docking studies further supported the biological results by revealing strong interactions with target enzymes. Overall, this work provides valuable insights into the development of new heterocyclic compounds with potential applications in agriculture and pharmaceutical fields.

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