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Heterocyclic Scaffolds in Drug Discovery

Heterocyclic Scaffolds in Drug Discovery

Paperback

Chemistry

ISBN10: 6209848230
ISBN13: 9786209848230
Publisher: LAP Lambert Academic Publishing
Published: Apr 15 2026
Pages: 84
Weight: 0.27
Height: 0.20 Width: 6.00 Depth: 9.00
Language: English
Heterocyclic compounds represent a fundamental class of molecules in medicinal chemistry due to their structural diversity and broad spectrum of biological activities. These frameworks are integral to a majority of therapeutic agents and play a crucial role in drug discovery and development. Among them, 1,2,3-Triazole, Benzimidazole, Thiazole, and Benzo[g]quinoline derivatives have gained considerable importance as key pharmacophore exhibiting antimicrobial, anticancer, anti-inflammatory, and antidiabetic properties.This book provides a comprehensive overview of synthetic methodologies for the construction of these heterocyclic systems, covering both classical and modern strategies. Emphasis is given to reaction mechanisms, strategic transformations, and recent advances in efficient and sustainable synthesis. The biological significance of these compounds is further explored through structure-activity relationships, supported by in vitro and in silico studies.Overall, this work integrates synthetic and biological perspectives to support research in medicinal chemistry.

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Chemistry