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Functional Analysis of Long Non-Coding Rnas: Methods and Protocols

Functional Analysis of Long Non-Coding Rnas: Methods and Protocols

Hardcover

Series: Methods in Molecular Biology, Book 2254

Genetics

ISBN10: 1071611577
ISBN13: 9781071611579
Publisher: Humana Pr
Published: Dec 17 2020
Pages: 351
Weight: 1.80
Height: 0.90 Width: 7.80 Depth: 10.30
Language: English
This detailed volume presents a comprehensive bioinformatic and experimental toolbox for prioritizing, annotating, and functionally analyzing long non-coding RNAs (lncRNAs). Playing a vital role in diverse biological progresses and human disease, lncRNAs have proven to be a challenging subject of study due to our limited understanding of their sequence-function relationships, lack of complete genetic annotation, and the unavailability of systems required to define their functional importance and molecular mechanisms, all of which this book seeks to address. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Genetics