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Epigenetics in Human Reproduction and Development

Epigenetics in Human Reproduction and Development

Hardcover

Medical ReferenceTechnology & EngineeringGenetics

ISBN10: 9813144262
ISBN13: 9789813144262
Publisher: World Scientific Publishing Company
Published: Feb 20 2017
Pages: 304
Weight: 1.35
Height: 0.70 Width: 6.10 Depth: 9.10
Language: English

Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood.

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