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Chromosome Segregation and Aneuploidy

Chromosome Segregation and Aneuploidy

Paperback

Series: NATO Asi Subseries H:, Book 72

Medical ReferenceChemistryGenetics

ISBN10: 3642849407
ISBN13: 9783642849404
Publisher: Springer Nature
Published: Jan 28 2012
Pages: 425
Weight: 1.38
Height: 0.91 Width: 6.14 Depth: 9.21
Language: English
Aneuploidy - the greatest genetic affliction of man - has its origin in manycellular processes. Its forerunner, chromosome non-disjunction, can result from malfunction of one of many processes involved in faithful segregation of chromosomes during mitosis or meiosis. Experts on chromosome biology, centromere, kinetochore, microtubules, spindle apparatus, biochemistry of mitosis and meiosis, developmental biology, and environmental mutagenesis discuss basic and applied aspects of how chromosomes malsegregate and how aneuplody originates. The most recent techniques employed to study chromosome segregation and also methods to determine aneugenic chemicals are described.

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