Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Chemogenomics and Chemical Genetics: A User's Introduction for Biologists, Chemists and Informaticians

Chemogenomics and Chemical Genetics: A User's Introduction for Biologists, Chemists and Informaticians

Marechal, Eric
Roy, Sylvaine
Lafanechère, Laurence

Paperback

BiologyGeneral ScienceGenetics

ISBN10: 3662519917
ISBN13: 9783662519912
Publisher: Springer Nature
Published: Aug 23 2016
Pages: 256
Weight: 1.05
Height: 0.57 Width: 7.00 Depth: 10.00
Language: English

Biological and chemical sciences have undergone an unprecedented transformation, reflected by the huge use of parallel and automated technologies in key fields such as genome sequencing, DNA chips, nanoscale functional biology or combinatorial chemistry. It is now possible to generate and store from tens of thousands to millions of new small molecules, based on enhanced chemical synthesis strategies. Automated screening of small molecules is one of the technologies that has revolutionized biology, first developed for the pharmaceutical industry and recently introduced in academic laboratories. High-throughput and high-content screening allow the identification of bioactive compounds in collections of molecules (chemical libraries), being effective on biological targets defined at various organisational scales, from proteins to cells to complete organisms. These bioactive molecules can be therapeutic drug candidates, molecules for biotech, diagnostic or agronomic applications, or tools for basic research. Handling a large number of biological (genomic and post-genomic), chemical and experimental information, screening approaches cannot be envisaged without any electronic storage and mathematical treatment of the data. Chemogenomics and Chemical Genetics is an introductory manual presenting methods and concepts making up the basis for this recent discipline.

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