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The Azide-Alkyne 1,3-dipolar Cycloaddition "Click Chemistry"

The Azide-Alkyne 1,3-dipolar Cycloaddition "Click Chemistry"

Paperback

Chemistry

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ISBN10: 384166105X
ISBN13: 9783841661050
Publisher: Ed Universitaires Europeennes
Published: Aug 10 2018
Pages: 84
Weight: 0.30
Height: 0.20 Width: 6.00 Depth: 9.00
Language: English
My researches, being done focus on the synthesis of a new series of 5-Chloroisatin derivatives using N-alkylation reactions under the conditions of phase transfer catalysis (PTC) by various alkylating agents, as well as that 1,3-dipolar cycloaddition reactions involving azides as dipoles on the dipolarophiles prepared previously, the structures of the various compounds obtained were determined spectroscopically (1H NMR, 13C NMR). Quantum chemistry calculations were used to study the reaction mechanisms and to interpret experimental results using the DFT/B3LYP/6-31G method.

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