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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Ureases: Functions, Classes, and Applications

Ureases: Functions, Classes, and Applications

Braun, Rodrigo Ligabu
R. Da S. Carlini, Celia Regina

Paperback

Series: Foundations and Frontiers in Enzymology

BiologyChemistry

Currently unavailable to order

ISBN10: 032391800X
ISBN13: 9780323918008
Publisher: Academic Press
Published: Feb 19 2024
Pages: 482
Language: English

Ureases: Foundations, Classes, and Applications provides a thorough, practical analysis of ureases--enzymes of growing relevance across a range of biotechnological applications and drug discovery. Unique in many aspects, ureases are one of the few enzymes to have nickel in their active sites. This book covers all aspects of this enzymatic class starting with foundational overview and then providing historical urease research and current state, from basic biochemistry to the use of ureases as hallmarks in enzymology, crystallography, and bioinorganic chemistry. The different classes of ureases, structurally diverse but chemically equivalent, are individually discussed.

The multi-protein, multi-step activation of ureases (with chemical modification of residues, transport, and transfer of nickel ions) are examined in-depth, along with the catalytic mechanisms of ureolysis and its inhibitors. The final two sections of the book address multiple applications of ureases in health and biotechnology, respectively, going from gastric ulcer treatment to architectural uses in buildings and engineering. Future applications and next steps in research are also considered.

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