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Therapeutic Oligonucleotides

Therapeutic Oligonucleotides

Paperback

Series: Annals of the New York Academy of Science, Book 1058

Medical ReferenceAnthropologyEvolution

ISBN10: 1573316091
ISBN13: 9781573316095
Publisher: John Wiley & Sons
Published: Jan 1 2006
Pages: 284
Weight: 0.84
Height: 0.60 Width: 6.00 Depth: 9.00
Language: English
The potential for the development of therapeutic oligonucleotides into clinical medicines and their use as basic research tools are explored in this volume, which is the proceedings of the 7th NIH Symposium on Therapeutic Oligonucleotides. The focus is on antisense, RNAi, triple-helix, gene repair, DNA chips, and CpG immune modulatory oligonucleotides.

Specific chapters address designing better siRNAs, splice switching oligonucleotides, selective delivery of oligonucleotides, and medicinal drugs by receptor-mediated endocytosis, development of a function overriding siRNA silencing in mammalian cells, transcription factor decoys, and modified oligonucleotide hybridization and genetic insertion.

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