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Tgf-β In Human Disease
Paperback
Medical ReferenceBiologyChemistry
ISBN13: 9784431546863
Publisher: Springer
Published: Jul 15 2015
Pages: 464
Weight: 1.45
Height: 0.95 Width: 6.14 Depth: 9.21
Language: English
Part I Introduction.- 1 Transforming Growth Factor-β Signaling.- 2 TGF-β Signaling in Stem Cell Fate Determination.- 3 Emerging Roles of TGF-β Co-receptors in Human Disease.- Part II Cancer, Fibrosis, and Inflammation.- 4 TGF-β in Cancer Stem Cells.- 5 TGF-β as Tumor Suppressor: In Vitro Mechanistic Aspects of Growth Inhibition.- 6 TGF-β as Tumor Suppressor: Lessons from Mouse Models.- 7 The Multifunctional Roles of TGF-β in Navigating the Metastatic Cascade.- 8 TGF-β Signaling in Leukemogenesis.- 9 TGF-β in Skin Cancer and Fibrosis.- 10 The Role of TGF-β in Cutaneous Melanoma Biology.- 11 The Transforming Growth Factor-Beta (TGF-β) in Liver Fibrosis.- 12 TGF-β and Inhibitory Smads in Inflammation.- Part III Cardiovascular Diseases.- 13 TGF-β and Cardiovascular Disorders.- 14 TGF-β Signaling in Physiological and Pathological Angiogenesis.- 15 TGF-β Signaling Pathway and MicroRNAs in Cardiovascular Disease.- Part IV Other Diseases.- 16 TGF-β and Genetic Skeletal Diseases.- 17 TGF-β in Brain Disorders.- 18 TGF-β and Metabolic Homeostasis.- Part V Disease Prognosis and Therapy. 19 Targeting Pro-Angiogenic TGF-β Signaling in the Tumor Microenvironment.
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