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Transporters as Targets for Drugs

Transporters as Targets for Drugs

Paperback

Series: Topics in Medicinal Chemistry, Book 4

BiologyChemistry

ISBN10: 3642099696
ISBN13: 9783642099694
Publisher: Springer Nature
Published: Oct 28 2010
Pages: 254
Weight: 0.84
Height: 0.56 Width: 6.14 Depth: 9.21
Language: English
Overview: Transporters as Targets for Drug Discovery.- Membrane Transporters: Structure, Function and Targets for Drug Design.- Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs.- Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter.- The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors.- Molecular Imaging of Transporters with Positron Emission Tomography.- Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c ?.- Glycine Transporters and Their Inhibitors.

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Chemistry