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Tetramer Stability and Functional Regulation of Tumor Suppressor Protein P53

Tetramer Stability and Functional Regulation of Tumor Suppressor Protein P53

Paperback

Series: Springer Theses

Chemistry

ISBN10: 4431547258
ISBN13: 9784431547259
Publisher: Springer Nature
Published: Aug 9 2014
Pages: 74
Weight: 0.30
Height: 0.18 Width: 6.14 Depth: 9.21
Language: English
Quantitative analysis for p53 tetramerization domain mutants reveals a low threshold for tumor suppressor inactivation.- Stabilization of mutant tetrameric structures by calixarene derivatives.- Inhibition of the transcriptional activity of p53 through hetero-oligomerization.

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