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612-822-4611
Staphylococcal Infections (Host and Pathogenic Factors)

Staphylococcal Infections (Host and Pathogenic Factors)

Hardcover

General Science

ISBN10: 303651418X
ISBN13: 9783036514185
Publisher: Mdpi Ag
Published: Nov 25 2021
Pages: 242
Weight: 1.59
Height: 0.81 Width: 6.69 Depth: 9.61
Language: English

Although 30% of the healthy human population is colonized with various Staphylococcus species, some staphylococcal strains, referred to as opportunistic pathogens, can cause minor to life-threatening diseases. The pathogenicity of these bacteria depends on their virulence factors and the robustness of the regulatory networks expressing these virulence factors. Virulence factors of pathogenic Staphylococcus spp. consist of numerous toxins, enterotoxins (some of which act as superantigens), enzymes, and proteins (cytoplasmic, extracellular, and surface) that are regulated by two-component (TC) and quorum-sensing (QS) regulatory networks. To enter this niche, some other Staphylococcus species, such as Staphylococcus simulans, produce a potent endopeptidase called lysostaphin, which can inhibit the growth of pathogenic S. aureus. Some other Staphylococcus species produce autolysins and cationic peptides to win the intra- and inter-species competition. The outcome of this microbial invasion depends not

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