Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Sister Chromatid Exchanges: 25 Years of Experimental Research Part B Genetic Toxicology and Human Studies

Sister Chromatid Exchanges: 25 Years of Experimental Research Part B Genetic Toxicology and Human Studies

Tice, Raymond

Paperback

Series: Basic Life Sciences, Book 29

Medical ReferenceLawns, Trees, & ShrubsOther Animals

ISBN10: 1468448943
ISBN13: 9781468448948
Publisher: Springer Nature
Published: Feb 16 2013
Pages: 1033
Weight: 1.94
Height: 1.14 Width: 6.69 Depth: 9.61
Language: English
Chromosomes, being well-defined structures that are easily vis- ible under the optical microscope, readily lend themselves to in- tense physical and biochemical study. The understanding of the structure and function of this most critical genetic material has progressed through a number of interesting stages. Often connected with the development of new techniques in staining and photography, using the standard microscope and the electron microscope. It is interesting to look back at the history of cytogenetics. I would like especially to emphasize the work of Karl Sax and many of his students. Work with Tradescantia became feasible after Edgar Anderson straightened out the ecology and Sax took advantage of the small number of chromosomes easily visible under the microscope. As a matter of fact, this development is seen as the foundation for the quantitative analysis of radiation effects on chromosomes. During the 50 years since then, more refined studies have been initiated. The study of cytogenetic mechanisms has become an important tool for the recognition of the effects of environmental factors on all liv- ing systems and has made SCE studies possible. One of the most important stages in chromosome research was the development, in radiation biology, of radiolabeling the chromosome with tritiated thymidine. This technique, published in 1957 by Dr.

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