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Single-Molecule Studies of Nucleic Acids and Their Proteins

Single-Molecule Studies of Nucleic Acids and Their Proteins

Hardcover

Series: Oxford Graduate Texts

BiologyPhysics

ISBN10: 0198530927
ISBN13: 9780198530923
Publisher: Oxford University Press
Published: Feb 20 2019
Pages: 240
Weight: 0.85
Height: 0.70 Width: 6.90 Depth: 9.80
Language: English
This book provides the basis for understanding the elastic properties of nucleic acids (DNA, RNA), the methods used to manipulate them (e.g. optical, magnetic and acoustic tweezers and traps), and how to observe their interactions with proteins (e.g. fluorescence microscopy, FCS, FRET, etc.). It then exemplifies the use of these various methods in the study of three families of DNA enzymes: polymerases, helicases and topoisomerases. The book aims not to be exhaustive, but rather to stimulate the imagination of readers in the application of these single molecule approaches to the study of DNA/RNA and their interactions.

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