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Rna-Based Mechanisms in Cancer

Rna-Based Mechanisms in Cancer

Hardcover

Medical ReferenceBiologyChemistry

ISBN10: 9811248656
ISBN13: 9789811248658
Publisher: World Scientific Publishing Company
Published: Oct 30 2023
Pages: 512
Weight: 1.88
Height: 1.13 Width: 6.00 Depth: 9.00
Language: English

The roles of gene transcription in cancer have long been appreciated. However, posttranscriptional processes also contribute significantly to alterations in gene expression that lead to tumor initiation, formation, and progression.


We have known for decades that alterations in the expression of key genes, such as those involved in cell proliferation, signaling, apoptosis, and immune responses, are major molecular events in cancer. This book presents our current understanding of selected posttranscriptional control mechanisms and the RNAs that they regulate. Each chapter provides an overview of a specific RNA-directed regulatory system and the RNA/protein factors involved, then discusses major findings in the field and their relationships to the development and/or treatment of cancer and associated diseases. Future questions serve to address where do we go from here and stimulate the reader's thinking about these important problems.

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