Sign-In
Cart
Role of Lysosomal Functions in Health and Disease
Hardcover
Series: Subcellular Biochemistry, Book 120
Medical ReferenceBiologyChemistry
ISBN13: 9783032421326
Publisher: Springer
Published: Feb 24 2027
Pages: 253
Language: English
This comprehensive book explores the multifaceted world of lysosomes, describing their critical roles in cellular functions and homeostasis, and human health. It begins with the fascinating journey of lysosome discovery, tracing early observations to groundbreaking research that unveiled their biogenesis and maintenance as well as their importance in cellular processes.
Readers will learn about the intricate pathways involved in lysosome formation and the transport mechanisms that ensure their proper function, including endocytosis and autophagy. The dynamic nature of lysosomes is highlighted, focusing on their ability to fuse with other organelles and reform, which is essential for maintaining their own homeostasis and ultimately that of cells.
The book explores how lysosomes play a pivotal role in sensing nutrients and regulating cellular metabolism, ensuring the balance and health of the cell. It delves into the genetic and transcriptional networks that govern lysosome maintenance and functionality, emphasizing the complexity of their regulation. Understanding the significance of lysosome positioning within cells and how their localization impacts their functional roles is another key aspect. Specialized regions where lysosome membranes interact with other organelles are discussed, facilitating communication and coordination within the cell.
The variation of lysosomal functions across different cell types is examined, highlighting the diversity and specialization of these organelles. The role of lysosomal ion channels in regulating cellular physiology, including their impact on ion homeostasis and signal transduction, is explored. Mechanisms by which cells respond to lysosomal damage, including repair processes and lysophagy, a specialized form of autophagy, are discussed. The consequences of lysosomal dysfunction are linked to various diseases such as neurodegenerative disorders and lysosomal storage diseases, as well as the aging process. Finally, the potential of targeting lysosomes for therapeutic interventions is explored, offering hope for treating diseases linked to lysosomal dysfunction.
This book is an essential resource for researchers, students, and professionals interested in cellular biology, pathology, and therapeutic development. It provides a thorough understanding of lysosomal functions beyond the degradation of intracellular and extracellular material, and their implications for health and disease.
Also in
Chemistry
Everything Is Tuberculosis: The History and Persistence of Our Deadliest Infection
Green, John
Hardcover
The Age of Alchemy: The Secret History of Chemistry from Ancient Magic to Modern Science
Chapman, Kit
Hardcover
The Iceman Inheritance: Prehistoric Sources of Western Man's Racism, Sexism and Aggression
Bradley, Michael
Paperback
Princeton Review AP Chemistry Premium Prep, 28th Edition: 7 Practice Tests + Digital Practice Online + Content Review
The Princeton Review
Paperback
AP Chemistry Premium, 2027: Prep Book with 6 Practice Tests + Comprehensive Review + Online Practice
Jespersen, Neil D., PH. D.
Kerrigan, Pamela, PH. D.
Paperback
5 Steps to a 5: AP Chemistry 2027: Practice AP Tests + AP Content Review + Digital Exams
Moore, John T.
Paperback
Liquid Rules: The Delightful and Dangerous Substances That Flow Through Our Lives
Miodownik, Mark
Paperback
BioGeometry Signatures: Harmonizing the Body's Subtle Energy Exchange with the Environment
Karim Dr Sc, Ibrahim
Paperback
The Flavor Matrix: The Art and Science of Pairing Common Ingredients to Create Extraordinary Dishes
Briscione, James
Parkhurst, Brooke
Hardcover
Herbal Pharmacy: The Science and Magic of Preparing and Administering Plant Medicine
Bancroft, Betzy
Paperback
Stuff Matters: Exploring the Marvelous Materials That Shape Our Man-Made World
Miodownik, Mark
Paperback
Liquid Soapmaking: Tips, Techniques and Recipes for Creating All Manner of Liquid and Soft Soap Naturally!
Thompson, Jackie
Paperback
Periodic Tales: A Cultural History of the Elements, from Arsenic to Zinc
Aldersey-Williams, Hugh
Paperback
The Color of North: The Molecular Language of Proteins and the Future of Life
Fink, Maggie M.
Rizk, Shahir S.
Hardcover
The One Thing You Need to Know: The Simple Way to Understand the Most Important Ideas in Science
Chown, Marcus
Paperback
Science and Cooking: Physics Meets Food, from Homemade to Haute Cuisine
Brenner, Michael
Sörensen, Pia
Weitz, David
Hardcover
Sciencia: Mathematics, Physics, Chemistry, Biology, and Astronomy for All
Tweed, Matt
Watkins, Matthew
Betts, Moff
Hardcover
The Telomere Effect: A Revolutionary Approach to Living Younger, Healthier, Longer
Blackburn, Elizabeth
Epel, Elissa
Paperback
Reactions: An Illustrated Exploration of Elements, Molecules, and Change in the Universe
Gray, Theodore
Paperback
Elements: A Visual Exploration of Every Known Atom in the Universe, Book 1 of 3
Gray, Theodore
Hardcover
Schaum's Outline of College Chemistry: 1,340 Solved Problems + 23 Videos
Epstein, Lawrence M.
Rosenberg, Jerome
Krieger, Peter
Paperback
Reactions: An Illustrated Exploration of Elements, Molecules, and Change in the Universe, Book 3 of 3
Gray, Theodore
Hardcover
Modern Quantum Chemistry: Introduction to Advanced Electronic Structure Theory
Szabo, Attila
Ostlund, Neil S.
Paperback
Schaum's Outline of Organic Chemistry, Sixth Edition
Sharefkin, Jacob
Meislich, Herbert
Nechamkin, Howard
Paperback
Physics and Chemistry Comic Book: Science Book for Kids Age 8-12 Comic Adventures & Fun Experiments
Bollino, Giulia
Paperback
Dopamina: Cómo Una Molécula Condiciona de Quién Nos Enamoramos, Con Quién Nos Acostamos, a Quién Votamos Y ... / The Molecule of More
Lieberman, Daniel Z.
Paperback
Exploring the World of Chemistry: From Ancient Metals to High-Speed Computers
Tiner, John Hudson
Paperback
An Introduction to Error Analysis, Third Edition: The Study of Uncertainties in Physical Measurements
Taylor, John R.
Paperback
Illustrated Guide to Home Chemistry Experiments: All Lab, No Lecture
Thompson, Robert Bruce
Paperback
Rocket Girl: The Story of Mary Sherman Morgan, America's First Female Rocket Scientist
Morgan, George D.
Paperback
Dopamina: Cómo Una Molécula Condiciona de Quién Nos Enamoramos, Con Quién Nos Acostamos, a Quién Votamos Y ... / The Molecule of More
Long, Michael E.
Lieberman, Daniel Z.
Paperback
The Elements: An Illustrated History of the Periodic Table (100 Ponderables) Revised and Updated
Jackson, Tom
Hardcover
Practice Makes Perfect Chemistry Review and Workbook, Second Edition
DeWane, Marian
Hattori, Heather
Paperback
Lippincott(r) Illustrated Reviews: Biochemistry
Franklin, David S.
Abali, Emine Ercikan
Cline, Susan D.
Paperback
The Science of Cleaning: Use the Power of Chemistry to Clean Smarter, Easier, and Safer-With Solutions for Every Kind of Dirt
Bressanini, Dario
Paperback
Revise IB: Biology Exam Practice Workbook - Higher Level (Second Edition)
Bragg, Sarah
Jaradat, Nadia
Paperback
Raising Elijah: Protecting Our Children in an Age of Environmental Crisis
Steingraber, Sandra
Paperback
Chemistry: Concepts and Problems, a Self-Teaching Guide
Snyder, Chad
Houk, Clifford C.
Post, Richard
Paperback
Schaum's Outline of General, Organic, and Biochemistry for Nursing and Allied Health
Odian, George
Blei, Ira
Paperback
Theory and Problems for Chemistry Olympiad: Challenging Concepts in Chemistry
Zhang, Sheng
Nan, Zhihan
Paperback
Dmt Extraction Guide: A Step-by-Step Guide to Safely Extracting DMT from Natural Sources at Home
J. Pare, Adell
Paperback
Quantum Mechanics, Volume 1: Basic Concepts, Tools, and Applications
Diu, Bernard
Laloë, Franck
Cohen-Tannoudji, Claude
Hardcover
Balancing Chemical Equations Worksheets (Over 200 Reactions to Balance): Chemistry Essentials Practice Workbook with Answers
McMullen, Chris
Paperback
La Solución de Los Telómeros: Aprende a Vivir Sano Y Feliz / The Telomere Effect
Epel, Elissa
Blackburn, Elizabeth
Paperback
Michael Faraday's The Chemical History of a Candle: With Guides to Lectures, Teaching Guides & Student Activities
Hammack, William S.
DeCoste, Donald J.
Paperback
The Mystery of Life's Origin: The Continuing Controversy
Olsen, Roger L.
Thaxton, Charles B.
Bradley, Walter L.
Paperback
Molecular Biology: Principles of Genome Function
Craig, Nancy L.
Green, Rachel R.
Greider, Carol C.
Paperback
Nature's Amazing Chemistry: Reflections on Its Complexity and Diversity
Freemantle, Michael
Hardcover
A Text Book of Physics and Chemistry for Nurses
Olive, Alfred Henderson
Bliss, Andrew Richard
Hardcover
Quantum Mechanics, Volume 3: Fermions, Bosons, Photons, Correlations, and Entanglement
Diu, Bernard
Laloë, Franck
Cohen-Tannoudji, Claude
Hardcover
The Shape of Data in Chemistry: An Introduction to Chemical Graph Theory and Topological Data Analysis
Clark, Aurora
Hardcover
Luminous Phenomena: A Story of Spontaneous Combustion, Phosphorescence and Other Cold Lights
Pentecost, Allan
Hardcover