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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
The Reticuloendothelial System in Health and Disease: Immunologic and Pathologic Aspects

The Reticuloendothelial System in Health and Disease: Immunologic and Pathologic Aspects

Escobar, Mario R.
Friedman, Herman
Reichard, Sherwood M.

Paperback

Series: Advances in Experimental Medicine and Biology, Book 73

AgricultureEnvironmental StudiesLawns, Trees, & Shrubs

ISBN10: 1468433024
ISBN13: 9781468433029
Publisher: Springer
Published: Dec 27 2012
Pages: 476
Weight: 1.94
Height: 1.03 Width: 7.00 Depth: 10.00
Language: English
An extraordinary development of the knowledge, concepts and biomedical applications has occurred during the past two decades in the biological sciences, including the Reticuloendothelial Sys- tem (RES). For example, it is now widely recognized that distinct classes of cells are involved in the recognition of exogenous invaders of the body such as microorganisms and other foreign an- tigens, as well as of endogenous parasites represented by trans- formed neoplastic cells and altered self antigens. Prominent among cell populations involved in such recognition of antigens and subsequent immune responses are those constituting the RES. In recent years, there has been much discussion and indeed contro- versy as to what constitutes such a system and even whether the term RES is appropriate. Some investigators feel that the phago- cytes are the most important cells of the RES as they playa major role in the defense mechanism of the host. Mononuclear phagocytes include tissue macrophages s well as circulating monocytes and their precursors. Although phagocytosis is a major functional ac- tivity, it is only one of their several functions. The important role of phagocytes and other mononuclear cells in antibody forma- tion, cell-mediated immunity, specific and non-specific resistance to microorganisms and tumor cells, as well as homeostatic adjust- ments in general has become the focus of attention for many inves- tigators.

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