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Regulatory Peptides and Cognate Receptors

Regulatory Peptides and Cognate Receptors

Paperback

Series: Results and Problems in Cell Differentiation, Book 26

Medical ReferenceAnthropologyBiology

ISBN10: 3662129086
ISBN13: 9783662129081
Publisher: Springer
Published: Oct 3 2013
Pages: 366
Weight: 1.18
Height: 0.79 Width: 6.14 Depth: 9.21
Language: English
In the last two decades, our knowledge on regulatory peptides and their cognate receptors, most of which are members of the seven transmembrane receptor families, has increased enormously. Regulatory peptides are small proteins which, besides their hormonal functions in regulating cellular metabolism in various tissues, may also act as neurotransmitters, and thus they often carry the prefix neuro. Many of the cognate receptors involved in transducing the peptidergic signal across the cell membrane via a family of G proteins exist in multiple forms, the number of which frequently exceeds that of the corresponding peptide ligands. In this book, various peptide-receptor systems are discussed, e.g. CRF, somatostatin, TRH, opioid peptides, vasopressin, and oxytocin. It also discusses new strategies such as reverse physiology to uncover new peptides and orphan receptors.

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Anthropology