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Protein Structure Prediction

Protein Structure Prediction

Hardcover

Series: Methods in Molecular Biology, Book 413

BiologyChemistry

ISBN10: 1588297527
ISBN13: 9781588297525
Publisher: Springer Nature
Published: Sep 12 2007
Pages: 337
Weight: 1.49
Height: 1.04 Width: 6.46 Depth: 9.16
Language: English

This book covers elements of both the data-driven comparative modeling approach to structure prediction and also recent attempts to simulate folding using explicit or simplified models. Despite the unsolved mystery of how a protein folds, advances are being made in predicting the interactions of proteins with other molecules, such as small ligands, nucleic acids or other proteins. Also rapidly advancing are the methods for solving the inverse folding problem, the problem of finding a sequence to fit a structure. This book focuses on the various computational methods for prediction, their successes and their limitations, from the perspective of their most well known practitioners.

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Chemistry