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Protein-Nanoparticle Interactions: The Bio-Nano Interface

Protein-Nanoparticle Interactions: The Bio-Nano Interface

Paperback

Series: Springer Biophysics, Book 15

Technology & EngineeringBiologyChemistry

ISBN10: 3642440681
ISBN13: 9783642440687
Publisher: Springer Nature
Published: Feb 8 2015
Pages: 84
Weight: 0.32
Height: 0.20 Width: 6.14 Depth: 9.21
Language: English

In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a biological identity to their surfaces (referred to as a corona), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called bio-nano interface, has been very rarely studied in detail to date, though the interest in this topic is rapidly growing.

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