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Phenotypic Screening: Methods and Protocols
Hardcover
Series: Methods in Molecular Biology, Book 1787
ISBN13: 9781493978465
Publisher: Humana Pr
Published: May 8 2018
Pages: 280
Weight: 1.60
Height: 0.69 Width: 7.00 Depth: 10.00
Language: English
1. Nutrient Stress Small-Molecule Screening Platform for Escherichia coli
Sara S. El Zahed, Garima Kumar, Madeline Tong, and Eric D. Brown
2. Validation and Development of an Escherichia coli Riboflavin Pathway Phenotypic Screen Hit as a Small-molecule Ligand of the Flavin Mononucleotide Riboswitch
Carl J. Balibar, Artjohn Villafania, Christopher M. Barbieri, Nick Murgolo, Terry Roemer, Hao Wang, and John A. Howe
3. Phenotypic Screening of Small Molecules with Anti-malarial Activity for Three Different Parasitic Life Stages
Nobutaka Kato, Sandra March, Sangeeta N Bhatia, and Matthias Marti
4. Phenotypic Screening for Inhibitors of a Mutant Thrombopoietin Receptor
Anna Ngo, Ann Koay, Christian Pecquet, Carmen C. Diaconu, David A. Jenkins, Andrew K. Shiau, Stefan N. Constantinescu, and Meng Ling Choong
5. A Cell-based Assay for Mitotic Spindle Orientation
Elina Glaubke and Holger Bastians
6. Isolation of Skeletal Muscle Stem Cells for Phenotypic Screens for Modulators of Proliferation
Andrew N. Billin and Aaron C. Hinken
7. Cell-based Methods to Identify Inducers of Human Pancreatic Beta-cell Proliferation
Courtney A. Ackeifi, Ethan A. Swartz, and Peng Wang
8. High-content Imaging Phenotypic Screen for Neurogenesis Using Primary Neural Progenitor Cells
Li Sharon Wu and Jingjun Li
9. Discovery of Modulators of Adipocyte Physiology Using Fully Functionalized Fragments
Andrea Galmozzi, Christopher G. Parker, Bernard P. Kok, Benjamin F. Cravatt, and Enrique Saez
10. The Ancient Genetic Networks of Obesity: Whole-animal Automated Screening for Conserved Fat Regulators
Wenfan Ke, Anna Drangowska-Way, Daniel Katz, Karsten Siller, and Eyleen J. O'Rourke
11. Modulation of Threat Response in Larval Zebrafish
Andrew J. Rennekamp
12. A PLA-iRoCS Pipeline for the Localization of Protein-Protein Interactions in situ
Taras Pasternak, William Teale, Thorsten Falk, Benedetto Ruperti, and Klaus Palme
13. High-Dimensional Profiling: The Theta Comparative Cell Scoring Method
Scott J Warchal, John C Dawson, and Neil O Carragher
14. Accessing the Open PHACTS Discovery Platform with Workflow Tools
Daniela Digles, Andrei Caracoti, and Edgar Jacoby
15. Quantitative Prioritization of Tool Compounds for Phenotypic Screening
Yuan Wang and Jeremy L. Jenkins
16. A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes
Mark E. Schurdak, Fen Pei, Timothy R. Lezon, Diane Carlisle, Robert Friedlander, D. Lansing Taylor, and Andrew M. Stern
17. Phenotype-based High-content Screening using Fluorescent Chemical Bioprobes: Lipid Droplets and Glucose Uptake Quantification in Live Cells
Young-Hee Shin and Seung Bum Park
18. Developing High-throughput Electrophysiological Assays for Phenotypic Screening
Jen Q. Pan, David Baez, Andrew Allen, and Hao-Ran Wang
19. Testing Susceptibility of Patient Derived Organoid Cultures to Therapies: Pharmacotyping
Richard A. Burkhart, Lindsey A. Baker, and Hervé Tiriac
20. &
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