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Intervenção das proantocianidinas da grainha de uva contra a toxicidade do cádmio
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ISBN10: 6209646093
ISBN13: 9786209646096
Publisher: Edicoes Nosso Conhecimento
Published: Mar 24 2026
Pages: 356
Weight: 1.05
Height: 0.79 Width: 6.00 Depth: 9.00
Language: Portuguese
ISBN13: 9786209646096
Publisher: Edicoes Nosso Conhecimento
Published: Mar 24 2026
Pages: 356
Weight: 1.05
Height: 0.79 Width: 6.00 Depth: 9.00
Language: Portuguese
Este livro trata do potencial impacto tóxico do metal pesado cádmio (Cd) através da indução de stress oxidativo e desequilÃbrio antioxidante em ratos e da sua atenuação por GSP. A relativa portabilidade do cádmio e a sua toxicidade inata para as formas vivas fazem dele um metal avassalador de preocupação toxicológica contÃnua. Os seres humanos modularam significativamente o ciclo biogeoquÃmico do Cd na Terra, mobilizando enormes quantidades de Cd na biosfera através da produção de metais não ferrosos e da combustão lenta de combustÃveis fósseis. Como resultado, os nossos ambientes estão significativamente enriquecidos com Cd. O prognóstico e o risco para a saúde do Cd mostram que é provável que este aumente no futuro e represente uma séria ameaça para a saúde humana devido aos seus efeitos deletérios. Assim, as medidas preventivas devem ser aperfeiçoadas para lutar contra esta grave ameaça. Embora tenham sido utilizados muitos agentes quelantes sintéticos para atenuar a toxicidade do Cd, estes têm sofrido efeitos secundários graves. As proantocianidinas de grainhas de uva (GSP), com as suas propriedades antioxidantes, proporcionam uma excelente defesa antioxidante, removendo o Cd do local da reação oxidante deletéria e conferindo proteção contra as manifestações tóxicas induzidas pelo Cd.
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