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Pharmaceutical grade paracetamol

Pharmaceutical grade paracetamol

Paperback

Chemistry

ISBN10: 620915641X
ISBN13: 9786209156410
Publisher: Our Knowledge Publishing
Published: Oct 27 2025
Pages: 60
Weight: 0.21
Height: 0.14 Width: 6.00 Depth: 9.00
Language: English
The aim of this project was to assess the pharmaceutical quality of 5 batches of paracetamol synthesized according to green chemistry principles, in compliance with European Pharmacopoeia requirements. These batches were characterized by qualitative and quantitative analyses: chromatography, infrared spectroscopy and differential scanning calorimetry. The most compliant batches were subjected to stability tests and forced degradation tests. Analyses confirmed the identity of the paracetamol synthesized, with FTIR correlations > 98%. HPLC-DAD purities were as high as 77.3%, and the batches selected (2 and 4) met pharmacopoeial standards (assay: 99.6-100.8%; K impurities

Also from

Sahbani, Amani

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Chemistry