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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems

Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems

Ondra, Thomas

Paperback

Series: Bestmasters

General MathematicsProbability & Statistics

ISBN10: 3658083433
ISBN13: 9783658083434
Publisher: Springer Nature
Published: Dec 18 2014
Pages: 102
Weight: 0.37
Height: 0.28 Width: 5.83 Depth: 8.27
Language: English
Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences.

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