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O-GlcNAcylation and Cancer

O-GlcNAcylation and Cancer

Hardcover

Genetics

ISBN10: 3036530835
ISBN13: 9783036530833
Publisher: Mdpi Ag
Published: Jan 31 2022
Pages: 114
Weight: 0.99
Height: 0.44 Width: 6.69 Depth: 9.61
Language: English

This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed.

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Genetics